Peroxisomes IPA: [pɛɜˈɹɒksɪˌsoʊmz] (also called microbo... -

Peroxisomes IPA: [pɛɜˈɹɒksɪˌsoʊmz] (also called microbo...

wikipedia - 12 Sep 2016
Peroxisomes IPA: [pɛɜˈɹɒksɪˌsoʊmz] (also called microbodies) are organelles found in virtually all eukaryotic cells. They are involved in catabolism of very long chain fatty acids, branched chain fatty acids, D-amino acids, and polyamines, reduction of reactive oxygen species – specifically hydrogen peroxide – and biosynthesis of plasmalogens, i.e. ether phospholipids critical for the normal function of mammalian brains and lungs. They also contain approximately 10% of the total activity

What do you know about Zellweger spectrum disorders?

Health Europa - 26 Oct 2018
Much progress in understanding the molecular defects and pathophysiology of peroxisomal disorders has been made by studying peroxisome function and biogenesis (i.e. assembly) in different cell models, through research with knock-out mouse models.

Expected Value Investing: Analyzing Genfit's Huge Potential

Seeking Alpha - 19 Oct 2018
Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) agonist aiming to treat NASH through a focus on NASH resolution. Thus far, the drug has completed one Phase 2 trial and is currently undergoing evaluation in Phase 3. Phase 2 Results.

Keeping out cancer

The Asian Age - 11 Nov 2018
Single nucleotide polymorphism (SNP) in genes NAT2 (N-acetyltransferase), interlukin-1B,GSTM1 and GSTT1 (Glutathione S-transferase), Pro12Ala peroxisome proliferator-activated receptor, COX (cyclooxygenase) have reported significant association in ...

CymaBay Therapeutics (CBAY) Shares Down 9.2%

Fairfield Current - 13 Nov 2018
Its lead product candidate is seladelpar, a selective agonist of peroxisome proliferator-activated receptor delta, which has completed Phase II clinical study for the treatment of primary biliary cholangitis, as well as patients with nonalcoholic ...

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